Phenomena and Processes

Parthanatos

A type of regulated cell death initiated by hyperactivation of POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1) as a consequence of DNA DAMAGE; OXIDATIVE STRESS; HYPOXIA; HYPOGLYCEMIA; or INFLAMMATION. This leads to DNA FRAGMENTATION and CHROMATIN condensation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A type of regulated cell death initiated by hyperactivation of POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1) as a consequence of DNA DAMAGE; OXIDATIVE STRESS; HYPOXIA; HYPOGLYCEMIA; or INFLAMMATION. This leads to DNA FRAGMENTATION and CHROMATIN condensation.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • PARP-1-Dependent Cell Death
  • PARP-Dependent Cell Death
  • Cell Death, PARP-1-Dependent
  • Cell Death, PARP-Dependent
  • PARP 1 Dependent Cell Death
  • PARP Dependent Cell Death

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2020

MeSH Record

Previous Indexing

  • Cell Death (2008-2019)

MeSH Hierarchy

Tree Number

  1. G04.146w.954w.750w

AMA Style

References

  1. National Library of Medicine. Parthanatos. Medical Subject Headings (MeSH). 2026. Unique ID D000079323. http://id.nlm.nih.gov/mesh/2026/D000079323
  2. Parthanatos. In: Wikipedia. https://en.wikipedia.org/wiki/Parthanatos
  3. Parthanatos. In: Wikidata. https://www.wikidata.org/wiki/Q25304429