Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Partial Thromboplastin Time

The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.

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Classification

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See Also

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Synonyms

9 entry terms
  • Activated Partial Thromboplastin Time
  • Thromboplastin Time, Partial
  • Cephalin-Kaolin Coagulation Time
  • Coagulation Time, Cephalin-Kaolin
  • Kaolin-Cephalin Coagulation Time
  • Cephalin Kaolin Coagulation Time
  • Coagulation Time, Cephalin Kaolin
  • Coagulation Time, Kaolin-Cephalin
  • Kaolin Cephalin Coagulation Time

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Aspects Covered

14 allowable subheadings

Indexed with the subheadings adverse effects, classification, economics, ethics, history, instrumentation, methods, mortality, nursing, psychology, standards, statistics & numerical data, trends, veterinary.

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Indexing Annotation

usually NIM

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History Note

91(80); was see under BLOOD COAGULATION TESTS 1980-90

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Previous Indexing

  • Blood Coagulation Tests (1966-1979)
  • Thromboplastin (1966-1979)

MeSH Hierarchy

Tree Numbers

  1. E01w.370.225.625.115w.600w
  2. E05.200.625.115w.600w
  3. G09.188.660w

AMA Style

References

  1. National Library of Medicine. Partial Thromboplastin Time. Medical Subject Headings (MeSH). 2026. Unique ID D010314. http://id.nlm.nih.gov/mesh/2026/D010314
  2. Partial Thromboplastin Time. In: Wikipedia. https://en.wikipedia.org/wiki/Partial_thromboplastin_time
  3. Partial Thromboplastin Time. In: Wikidata. https://www.wikidata.org/wiki/Q1755136