Structured Summary
Abstract
A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.
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Synonyms
2 entry terms
- Protein Aggregation, Pathological
- Aggregation, Pathological Protein
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Aspects Covered
35 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
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History Note
2015
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References
- National Library of Medicine. Pathological Protein Aggregation. Medical Subject Headings (MeSH). 2026. Unique ID D066263. http://id.nlm.nih.gov/mesh/2026/D066263
- Pathological Protein Aggregation. In: Wikipedia. https://en.wikipedia.org/wiki/Aggresome
- Pathological Protein Aggregation. In: Wikidata. https://www.wikidata.org/wiki/Q4692265