Chemicals and Drugs

Penicillin G

A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.

Chemical Identity

Chemical Information

Molecular Formula
C16H18N2O4S
Molecular Weight
334.4 g/mol
CAS Registry No.
61-33-6
IUPAC Name
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChIKey
JGSARLDLIJGVTE-MBNYWOFBSA-N
SMILES
CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C
MeSH Unique ID
D010400
Source
PubChem CID 5904

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

25 entry terms
  • Benzylpenicillin
  • Benpen
  • Benzylpenicillin Potassium
  • Coliriocilina
  • Crystapen
  • Or-pen
  • Parcillin
  • Pekamin
  • Pengesod
  • Penibiot
  • Penicilina G Llorente
  • Penicillin G Jenapharm
  • Penicillin G Potassium
  • Penicillin G Sodium
  • Penicillin Grünenthal
  • Penilevel
  • Peniroger
  • Pfizerpen
  • Sodiopen
  • Sodipen
  • Sodium Benzylpenicillin
  • Sodium Penicillin
  • Unicilina
  • Ursopen
  • Van-Pen-G

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.750w.750w
  2. D02w.886w.108w.750w.750w
  3. D03w.633.100.300w.750w.750w

MeSH Record

NLM Classification

QV 354

AMA Style

References

  1. National Library of Medicine. Penicillin G. Medical Subject Headings (MeSH). 2026. Unique ID D010400. http://id.nlm.nih.gov/mesh/2026/D010400
  2. Penicillin G. In: Wikipedia. https://en.wikipedia.org/wiki/Benzylpenicillin
  3. Penicillin G. In: Wikidata. https://www.wikidata.org/wiki/Q258450
  4. Penicillin G. In: PubChem Compound. CID 5904. https://pubchem.ncbi.nlm.nih.gov/compound/5904