Structured Summary
Abstract
The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Chemical Identity
Chemical Information
- Molecular Formula
- C19H27NO
- Molecular Weight
- 285.4 g/mol
- CAS Registry No.
- 359-83-1
- IUPAC Name
- (1R,9R,13R)-1,13-dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
- InChIKey
- VOKSWYLNZZRQPF-GDIGMMSISA-N
- SMILES
- C[C@H]1[C@H]2CC3=C([C@@]1(CCN2CC=C(C)C)C)C=C(C=C3)O
- MeSH Unique ID
- D010423
- Source
- PubChem CID 441278
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- Fortral
- Lexir
- Pentazocine Hydrochloride
- Pentazocine Lactate
- Talwin
- Hydrochloride, Pentazocine
- Lactate, Pentazocine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
66(64)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QV 89
AMA Style
References
- National Library of Medicine. Pentazocine. Medical Subject Headings (MeSH). 2026. Unique ID D010423. http://id.nlm.nih.gov/mesh/2026/D010423
- Pentazocine. In: Wikipedia. https://en.wikipedia.org/wiki/Pentazocine
- Pentazocine. In: Wikidata. https://www.wikidata.org/wiki/Q415793
- Pentazocine. In: PubChem Compound. CID 441278. https://pubchem.ncbi.nlm.nih.gov/compound/441278