Chemicals and Drugs

Pentobarbital

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)

Chemical Identity

Chemical Information

Molecular Formula
C11H18N2O3
Molecular Weight
226.27 g/mol
CAS Registry No.
76-74-4
IUPAC Name
5-ethyl-5-pentan-2-yl-1,3-diazinane-2,4,6-trione
InChIKey
WEXRUCMBJFQVBZ-UHFFFAOYSA-N
SMILES
CCCC(C)C1(C(=O)NC(=O)NC1=O)CC
MeSH Unique ID
D010424
Source
PubChem CID 4737

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Mebubarbital
  • Pentobarbitone
  • Diabutal
  • Etaminal
  • Ethaminal
  • Mebumal
  • Nembutal
  • Pentobarbital Sodium
  • Pentobarbital, Monosodium Salt
  • Sagatal
  • Monosodium Salt Pentobarbital

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

  1. D03w.383.742.698.253w.593w

AMA Style

References

  1. National Library of Medicine. Pentobarbital. Medical Subject Headings (MeSH). 2026. Unique ID D010424. http://id.nlm.nih.gov/mesh/2026/D010424
  2. Pentobarbital. In: Wikipedia. https://en.wikipedia.org/wiki/Pentobarbital
  3. Pentobarbital. In: Wikidata. https://www.wikidata.org/wiki/Q409632
  4. Pentobarbital. In: PubChem Compound. CID 4737. https://pubchem.ncbi.nlm.nih.gov/compound/4737