Chemicals and Drugs

Pepsinogens

Proenzymes secreted by chief cells, mucous neck cells, and pyloric gland cells, which are converted into pepsin in the presence of gastric acid or pepsin itself. (Dorland, 28th ed) In humans there are 2 related pepsinogen systems: PEPSINOGEN A (formerly pepsinogen I or pepsinogen) and PEPSINOGEN C (formerly pepsinogen II or progastricsin). Pepsinogen B is the name of a pepsinogen from pigs.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Proenzymes secreted by chief cells, mucous neck cells, and pyloric gland cells, which are converted into pepsin in the presence of gastric acid or pepsin itself. (Dorland, 28th ed) In humans there are 2 related pepsinogen systems: PEPSINOGEN A (formerly pepsinogen I or pepsinogen) and PEPSINOGEN C (formerly pepsinogen II or progastricsin). Pepsinogen B is the name of a pepsinogen from pigs.

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Synonyms

1 entry terms
  • Pepsinogen B

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Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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Indexing Annotation

do not confuse with PEPSINOGEN see PEPSINOGEN A

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History Note

99(72)

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Previous Indexing

  • Enzyme Precursors (1966-1971)
  • Pepsin (1966-1971)
  • Pepsinogen (1972-1998)

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References

  1. National Library of Medicine. Pepsinogens. Medical Subject Headings (MeSH). 2026. Unique ID D010435. http://id.nlm.nih.gov/mesh/2026/D010435
  2. Pepsinogens. In: Wikidata. https://www.wikidata.org/wiki/Q381857