Structured Summary
Abstract
DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers.
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Classification
Broader headings
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MeSH Record
Synonyms
5 entry terms
- Peptide Nucleic Acid
- Acid, Peptide Nucleic
- Acids, Peptide Nucleic
- Nucleic Acid, Peptide
- Nucleic Acids, Peptide
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
1999
MeSH Record
Previous Indexing
- Nucleic Acids (1981-1998)
- Peptides (1993-1998)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Peptide Nucleic Acids. Medical Subject Headings (MeSH). 2026. Unique ID D020135. http://id.nlm.nih.gov/mesh/2026/D020135
- Peptide Nucleic Acids. In: Wikipedia. https://en.wikipedia.org/wiki/Peptide_nucleic_acid
- Peptide Nucleic Acids. In: Wikidata. https://www.wikidata.org/wiki/Q412152