Structured Summary
Abstract
A long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES.
Chemical Identity
Chemical Information
- Molecular Formula
- C19H26N2S
- Molecular Weight
- 314.5 g/mol
- CAS Registry No.
- 66104-22-1
- IUPAC Name
- (6aR,9R,10aR)-9-(methylsulfanylmethyl)-7-propyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline
- InChIKey
- YEHCICAEULNIGD-MZMPZRCHSA-N
- SMILES
- CCCN1C[C@@H](C[C@H]2[C@H]1CC3=CNC4=CC=CC2=C34)CSC
- MeSH Unique ID
- D010479
- Source
- PubChem CID 47811
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
10 entry terms
- Celance
- LY-127,809
- LY-127809
- Parkotil
- Pergolide Mesylate
- Permax
- Pharken
- LY127,809
- LY127809
- Mesylate, Pergolide
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
87
MeSH Record
Previous Indexing
- Ergolines (1969-1986)
- Ergot Alkaloids (1966-1986)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Pergolide. Medical Subject Headings (MeSH). 2026. Unique ID D010479. http://id.nlm.nih.gov/mesh/2026/D010479
- Pergolide. In: Wikipedia. https://en.wikipedia.org/wiki/Pergolide
- Pergolide. In: Wikidata. https://www.wikidata.org/wiki/Q415752
- Pergolide. In: PubChem Compound. CID 47811. https://pubchem.ncbi.nlm.nih.gov/compound/47811