Chemicals and Drugs

Perilipin-1

A lipid droplet protein that is expressed primarily by ADIPOCYTES of WHITE ADIPOSE TISSUE and BROWN ADIPOSE TISSUE. It co-localizes with MACROPHAGES and FOAM CELLS of artherosclerotic lesions and stabilizes LIPID DROPLETS by inhibiting HORMONE SENSITIVE LIPASE. It may also protect TRIGLYCERIDES against hydrolysis within the PLASMA MEMBRANE and modulate CHOLESTEROL ESTER HYDROLASE activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A lipid droplet protein that is expressed primarily by ADIPOCYTES of WHITE ADIPOSE TISSUE and BROWN ADIPOSE TISSUE. It co-localizes with MACROPHAGES and FOAM CELLS of artherosclerotic lesions and stabilizes LIPID DROPLETS by inhibiting HORMONE SENSITIVE LIPASE. It may also protect TRIGLYCERIDES against hydrolysis within the PLASMA MEMBRANE and modulate CHOLESTEROL ESTER HYDROLASE activity.

MeSH Record

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Broader headings

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MeSH Record

Synonyms

12 entry terms
  • PERI Protein
  • Perilipin
  • Perilipin A Protein
  • Perilipin B Protein
  • Perilipin Protein
  • Plin Protein
  • Perilipin 1
  • Protein, PERI
  • Protein, Perilipin
  • Protein, Perilipin A
  • Protein, Perilipin B
  • Protein, Plin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1991)

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AMA Style

References

  1. National Library of Medicine. Perilipin-1. Medical Subject Headings (MeSH). 2026. Unique ID D000070778. http://id.nlm.nih.gov/mesh/2026/D000070778
  2. Perilipin-1. In: Wikipedia. https://en.wikipedia.org/wiki/Perilipin-1
  3. Perilipin-1. In: Wikidata. https://www.wikidata.org/wiki/Q415624