Structured Summary
Abstract
A perilipin that is expressed by many different cell types. It binds FATTY ACIDS and CHOLESTEROL, stabilizes TRIGLYCERIDES, and localizes to both the surface and hydrophobic core of LIPID DROPLETS, as well as the ENDOPLASMIC RECTICULUM and PLASMA MEMBRANE in MACROPHAGES. It also plays a central role in the biogenesis of lipid droplets and FOAM CELLS and is highly expressed by macrophages at atherosclerotic lesions in human arteries along with the INFLAMMATION markers TNF-ALPHA; MCP-1 RECEPTOR; and IL-6.
MeSH Record
Classification
Broader headings
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MeSH Record
Synonyms
10 entry terms
- ADRP Protein
- Adipophilin
- Adipose Differentiation-Related Protein
- PLIN2 Protein
- Perilipin 2 Protein
- Adipose Differentiation Related Protein
- Perilipin 2
- Protein, Adipose Differentiation-Related
- Protein, PLIN2
- Protein, Perilipin 2
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017 (1998)
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AMA Style
References
- National Library of Medicine. Perilipin-2. Medical Subject Headings (MeSH). 2026. Unique ID D000070780. http://id.nlm.nih.gov/mesh/2026/D000070780
- Perilipin-2. In: Wikidata. https://www.wikidata.org/wiki/Q21134178