Chemicals and Drugs

Perilipin-4

A perilipin protein characterized by an extensive 11-mer repeat region, which forms five adjacent alpha-helices. It is expressed primarily in WHITE ADIPOSE TISSUE and differentiating ADIPOCYTES, as well as skeletal muscle and heart. It is soluble in the cytoplasm but re-localizes to the surface of LIPID DROPLETS under high lipid conditions.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A perilipin protein characterized by an extensive 11-mer repeat region, which forms five adjacent alpha-helices. It is expressed primarily in WHITE ADIPOSE TISSUE and differentiating ADIPOCYTES, as well as skeletal muscle and heart. It is soluble in the cytoplasm but re-localizes to the surface of LIPID DROPLETS under high lipid conditions.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

4 entry terms
  • Perilipin 4 Protein
  • Plin4 Protein
  • S3-12 Protein
  • Perilipin 4

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Carrier Proteins (2004-2016)
  • Membrane Proteins (2004-2016)
  • Phosphoproteins (2004-2016)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Perilipin-4. Medical Subject Headings (MeSH). 2026. Unique ID D000071229. http://id.nlm.nih.gov/mesh/2026/D000071229
  2. Perilipin-4. In: Wikidata. https://www.wikidata.org/wiki/Q21123278