Chemicals and Drugs

Phosphatidylinositol 3-Kinases

Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.

MeSH Record

Classification

Broader headings

Narrower headings

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MeSH Record

Synonyms

22 entry terms
  • PI 3-Kinase
  • PI-3 Kinase
  • PI-3K
  • PI3 Kinases
  • PI3-Kinase
  • Phosphatidylinositol-3-OH Kinase
  • Phosphoinositide 3 Kinases
  • Phosphoinositide 3-Hydroxykinase
  • PtdIns 3-Kinase
  • PtdIns 3-Kinases
  • 3-Hydroxykinase, Phosphoinositide
  • Kinase, PI-3
  • Kinase, Phosphatidylinositol-3-OH
  • Kinases, PI3
  • Kinases, Phosphoinositide 3
  • PI 3 Kinase
  • PI3 Kinase
  • Phosphatidylinositol 3 Kinases
  • Phosphatidylinositol 3 OH Kinase
  • Phosphoinositide 3 Hydroxykinase
  • PtdIns 3 Kinase
  • PtdIns 3 Kinases

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

note specifics including PHOSPHATIDYLINOSITOL 3-KINASE are available

MeSH Record

History Note

2011(1998)

MeSH Record

Previous Indexing

  • Phosphotransferases (1988-1993)
  • Phosphotransferases (Alcohol Group Acceptor) (1994-1997)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.500w
  2. D12.776w.476.556w

AMA Style

References

  1. National Library of Medicine. Phosphatidylinositol 3-Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D019869. http://id.nlm.nih.gov/mesh/2026/D019869
  2. Phosphatidylinositol 3-Kinases. In: Wikipedia. https://en.wikipedia.org/wiki/Phosphoinositide_3-kinase
  3. Phosphatidylinositol 3-Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q423725