Chemicals and Drugs

Phosphoribosyl Pyrophosphate

The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.

Chemical Identity

Chemical Information

Molecular Formula
C5H13O14P3
Molecular Weight
390.07 g/mol
CAS Registry No.
7540-64-9
IUPAC Name
[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl] phosphono hydrogen phosphate
InChIKey
PQGCEDQWHSBAJP-TXICZTDVSA-N
SMILES
C([C@@H]1[C@H]([C@H]([C@H](O1)OP(=O)(O)OP(=O)(O)O)O)O)OP(=O)(O)O
MeSH Unique ID
D010754
Source
PubChem CID 7339

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

1 entry terms
  • Pyrophosphate, Phosphoribosyl

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under PENTOSEPHOSPHATES 1975-90

MeSH Record

Previous Indexing

  • Organophosphorus Compounds (1972-1974)
  • Pentosephosphates (1972-1974)
  • Pyrophosphoric Acids (1972-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Phosphoribosyl Pyrophosphate. Medical Subject Headings (MeSH). 2026. Unique ID D010754. http://id.nlm.nih.gov/mesh/2026/D010754
  2. Phosphoribosyl Pyrophosphate. In: Wikipedia. https://en.wikipedia.org/wiki/Phosphoribosyl_pyrophosphate
  3. Phosphoribosyl Pyrophosphate. In: Wikidata. https://www.wikidata.org/wiki/Q420633
  4. Phosphoribosyl Pyrophosphate. In: PubChem Compound. CID 7339. https://pubchem.ncbi.nlm.nih.gov/compound/7339