Chemicals and Drugs

Phosphoribosylglycinamide Formyltransferase

An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-phospho-D-ribosyl)glycinamide to yield N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and tetrahydrofolate. It plays a role in the de novo purine biosynthetic pathway.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-phospho-D-ribosyl)glycinamide to yield N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and tetrahydrofolate. It plays a role in the de novo purine biosynthetic pathway.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

18 entry terms
  • 2-Amino-N-Ribosylacetamide 5'-Phosphate Transformylase
  • 5'-Phosphoribosylglycinamide Transformylase
  • GAR Formyltransferase
  • GAR Transformylase
  • GARTFase
  • Glycinamide Ribonucleotide Transformylase
  • Glycinamideribotide Transformylase
  • 2 Amino N Ribosylacetamide 5' Phosphate Transformylase
  • 5' Phosphoribosylglycinamide Transformylase
  • 5'-Phosphate Transformylase, 2-Amino-N-Ribosylacetamide
  • Formyltransferase, GAR
  • Formyltransferase, Phosphoribosylglycinamide
  • Ribonucleotide Transformylase, Glycinamide
  • Transformylase, 2-Amino-N-Ribosylacetamide 5'-Phosphate
  • Transformylase, 5'-Phosphoribosylglycinamide
  • Transformylase, GAR
  • Transformylase, Glycinamide Ribonucleotide
  • Transformylase, Glycinamideribotide

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1980); use ACYLTRANSFERASES 1979, GLYCINE 1974-1979, FORMIC ACIDS 1974-1979, PENTOSEPHOSPHATES 1974-1975, RIBOSEMONOPHOSPHATES 1975-1979, & TRANSFERASES 1974-1978

MeSH Hierarchy

Tree Number

  1. D08.811w.913w.555.400.750w

AMA Style

References

  1. National Library of Medicine. Phosphoribosylglycinamide Formyltransferase. Medical Subject Headings (MeSH). 2026. Unique ID D051026. http://id.nlm.nih.gov/mesh/2026/D051026
  2. Phosphoribosylglycinamide Formyltransferase. In: Wikipedia. https://en.wikipedia.org/wiki/Phosphoribosylglycinamide_formyltransferase
  3. Phosphoribosylglycinamide Formyltransferase. In: Wikidata. https://www.wikidata.org/wiki/Q5162796