Structured Summary
Abstract
A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
Chemical Identity
Chemical Information
- Molecular Formula
- C15H21N3O2
- Molecular Weight
- 275.35 g/mol
- CAS Registry No.
- 57-47-6
- IUPAC Name
- [(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate
- InChIKey
- PIJVFDBKTWXHHD-HIFRSBDPSA-N
- SMILES
- C[C@@]12CCN([C@@H]1N(C3=C2C=C(C=C3)OC(=O)NC)C)C
- MeSH Unique ID
- D010830
- Source
- PubChem CID 5983
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
1 entry terms
- Eserine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QV 124
AMA Style
References
- National Library of Medicine. Physostigmine. Medical Subject Headings (MeSH). 2026. Unique ID D010830. http://id.nlm.nih.gov/mesh/2026/D010830
- Physostigmine. In: Wikipedia. https://en.wikipedia.org/wiki/Physostigmine
- Physostigmine. In: Wikidata. https://www.wikidata.org/wiki/Q410595
- Physostigmine. In: PubChem Compound. CID 5983. https://pubchem.ncbi.nlm.nih.gov/compound/5983