Diseases

Pick Disease of the Brain

A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

16 entry terms
  • Brain Atrophy, Circumscribed Lobar
  • Circumscribed Lobar Atrophy of the Brain
  • Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions
  • Lobar Atrophy (Brain)
  • Lobar Atrophy Of Brain
  • Lobar Atrophy of the Brain
  • Pick Disease
  • Pick Disease Of Brain
  • Pick's Disease
  • Picks Disease of Brain
  • Atrophies, Lobar (Brain)
  • Atrophy, Lobar (Brain)
  • Disease, Pick
  • Disease, Pick's
  • Lobar Atrophies (Brain)
  • Picks Disease

MeSH Record

Aspects Covered

31 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, rehabilitation, surgery, therapy, urine, virology.

MeSH Record

History Note

2000; for PICKS DISEASE OF BRAIN use DEMENTIA 1992-1999

MeSH Record

Previous Indexing

  • Dementia (1966-1999)

MeSH Hierarchy

Tree Numbers

  1. C10w.228w.140w.380w.266w.299w.500w
  2. F03w.615w.400w.380w.299w.500w

AMA Style

References

  1. National Library of Medicine. Pick Disease of the Brain. Medical Subject Headings (MeSH). 2026. Unique ID D020774. http://id.nlm.nih.gov/mesh/2026/D020774
  2. Pick Disease of the Brain. In: Wikipedia. https://en.wikipedia.org/wiki/Pick%27s_disease
  3. Pick Disease of the Brain. In: Wikidata. https://www.wikidata.org/wiki/Q18576