Diseases

Piebaldism

Autosomal dominant, congenital disorder characterized by localized hypomelanosis of the skin and hair. The most familiar feature is a white forelock presenting in 80 to 90 percent of the patients. The underlying defect is possibly related to the differentiation and migration of melanoblasts, as well as to defective development of the neural crest (neurocristopathy). Piebaldism may be closely related to WAARDENBURG SYNDROME.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Autosomal dominant, congenital disorder characterized by localized hypomelanosis of the skin and hair. The most familiar feature is a white forelock presenting in 80 to 90 percent of the patients. The underlying defect is possibly related to the differentiation and migration of melanoblasts, as well as to defective development of the neural crest (neurocristopathy). Piebaldism may be closely related to WAARDENBURG SYNDROME.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

8 entry terms
  • Piebald Trait
  • Piebald Traits
  • Trait, Piebald
  • Traits, Piebald
  • Albinism, Cutaneous
  • Albinism, Partial
  • Cutaneous Albinism
  • Partial Albinism

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

91

MeSH Record

Previous Indexing

  • Albinism (1966-1971)
  • Pigmentation Disorders (1966-1990)

MeSH Hierarchy

Tree Numbers

  1. C16w.320w.290.040w.600w
  2. C16w.320w.565w.100.102w.600w
  3. C16w.320w.850w.080w.600w
  4. C17.800w.621w.440w.102w.600w
  5. C17.800w.827w.080w.600w
  6. C18.452w.648w.100.102w.600w

AMA Style

References

  1. National Library of Medicine. Piebaldism. Medical Subject Headings (MeSH). 2026. Unique ID D016116. http://id.nlm.nih.gov/mesh/2026/D016116
  2. Piebaldism. In: Wikipedia. https://en.wikipedia.org/wiki/Piebaldism
  3. Piebaldism. In: Wikidata. https://www.wikidata.org/wiki/Q1516083