Chemicals and Drugs

Piribedil

A dopamine D2 agonist. It is used in the treatment of parkinson disease, particularly for alleviation of tremor. It has also been used for circulatory disorders and in other applications as a D2 agonist.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A dopamine D2 agonist. It is used in the treatment of parkinson disease, particularly for alleviation of tremor. It has also been used for circulatory disorders and in other applications as a D2 agonist.

Chemical Identity

Chemical Information

Molecular Formula
C16H18N4O2
Molecular Weight
298.34 g/mol
CAS Registry No.
3605-01-4
IUPAC Name
2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine
InChIKey
OQDPVLVUJFGPGQ-UHFFFAOYSA-N
SMILES
C1CN(CCN1CC2=CC3=C(C=C2)OCO3)C4=NC=CC=N4
MeSH Unique ID
D010891
Source
PubChem CID 4850

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • Piribendyl
  • ET-495
  • EU-4200
  • Piribedil Hydrochloride
  • Piribedil Mesylate
  • Piribedil Mono-hydrochloride
  • Trivastal
  • ET 495
  • ET495
  • EU 4200
  • EU4200
  • Hydrochloride, Piribedil
  • Mesylate, Piribedil
  • Mono-hydrochloride, Piribedil
  • Piribedil Mono hydrochloride

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under PIPERAZINES 1975-90

MeSH Record

Previous Indexing

  • Dioxoles (1971-1974)
  • Piperazines (1971-1974)
  • Pyrimidines (1971-1974)

MeSH Hierarchy

Tree Number

  1. D03w.383.606w.790w

AMA Style

References

  1. National Library of Medicine. Piribedil. Medical Subject Headings (MeSH). 2026. Unique ID D010891. http://id.nlm.nih.gov/mesh/2026/D010891
  2. Piribedil. In: Wikipedia. https://en.wikipedia.org/wiki/Piribedil
  3. Piribedil. In: Wikidata. https://www.wikidata.org/wiki/Q413976
  4. Piribedil. In: PubChem Compound. CID 4850. https://pubchem.ncbi.nlm.nih.gov/compound/4850