Chemicals and Drugs

Piroxicam

A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.

Chemical Identity

Chemical Information

Molecular Formula
C15H13N3O4S
Molecular Weight
331.3 g/mol
CAS Registry No.
36322-90-4
IUPAC Name
4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1lambda6,2-benzothiazine-3-carboxamide
InChIKey
QYSPLQLAKJAUJT-UHFFFAOYSA-N
SMILES
CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3
MeSH Unique ID
D010894
Source
PubChem CID 54676228

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • CP-16171
  • Feldene
  • CP 16171
  • CP16171

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Thiazines (1966-1986)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QV 95

AMA Style

References

  1. National Library of Medicine. Piroxicam. Medical Subject Headings (MeSH). 2026. Unique ID D010894. http://id.nlm.nih.gov/mesh/2026/D010894
  2. Piroxicam. In: Wikipedia. https://en.wikipedia.org/wiki/Piroxicam
  3. Piroxicam. In: Wikidata. https://www.wikidata.org/wiki/Q408676
  4. Piroxicam. In: PubChem Compound. CID 54676228. https://pubchem.ncbi.nlm.nih.gov/compound/54676228