Chemicals and Drugs

Platelet Endothelial Cell Adhesion Molecule-1

A cell adhesion molecule, composed of a series of Ig-like domains, and expressed on virtually all MONOCYTES; PLATELETS; and GRANULOCYTES. PECAM-1 is highly expressed on endothelial cells and concentrated at the junctions between them. It is essential for TRANSENDOTHELIAL MIGRATION of leukocytes and removal of apoptotic cells by PHAGOCYTES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cell adhesion molecule, composed of a series of Ig-like domains, and expressed on virtually all MONOCYTES; PLATELETS; and GRANULOCYTES. PECAM-1 is highly expressed on endothelial cells and concentrated at the junctions between them. It is essential for TRANSENDOTHELIAL MIGRATION of leukocytes and removal of apoptotic cells by PHAGOCYTES.

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Classification

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Synonyms

6 entry terms
  • Antigens, CD31
  • CD31 Antigen
  • CD31 Antigens
  • PECAM-1
  • Antigen, CD31
  • Platelet Endothelial Cell Adhesion Molecule 1

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018 (1990)

MeSH Record

Previous Indexing

  • Antigens, Differentiation, Myelomonocytic (1990-1996)
  • Cell Adhesion Molecules (1995-1996)
  • Membrane Glycoproteins (1990-1994)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.200w.131w
  2. D12.776w.395w.550w.200w.131w
  3. D12.776w.543w.550w.200w.131w
  4. D23.050w.301.264.900.131w
  5. D23.050w.301.350w.131w
  6. D23.101w.100.900.131w

AMA Style

References

  1. National Library of Medicine. Platelet Endothelial Cell Adhesion Molecule-1. Medical Subject Headings (MeSH). 2026. Unique ID D019408. http://id.nlm.nih.gov/mesh/2026/D019408
  2. Platelet Endothelial Cell Adhesion Molecule-1. In: Wikipedia. https://en.wikipedia.org/wiki/CD31
  3. Platelet Endothelial Cell Adhesion Molecule-1. In: Wikidata. https://www.wikidata.org/wiki/Q4046167