Chemicals and Drugs

Plectin

A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and ACTIN CYTOSKELETON and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and ACTIN CYTOSKELETON and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • 500-kDa HD1 Protein
  • Hemidesmosomal Protein HD1
  • 500 kDa HD1 Protein
  • HD1 Protein, 500-kDa
  • HD1, Hemidesmosomal Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1982)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.220.790w.750
  2. D12.776w.744w.736

AMA Style

References

  1. National Library of Medicine. Plectin. Medical Subject Headings (MeSH). 2026. Unique ID D051190. http://id.nlm.nih.gov/mesh/2026/D051190
  2. Plectin. In: Wikidata. https://www.wikidata.org/wiki/Q24776953