Anatomy

Podosomes

Actin-rich adhesive structures found at the ventral surface of metazoan ENDOTHELIAL CELLS. When found in cultured cancer cells they are referred to as invadopodia. These are matrix-degrading structures composed of an ACTIN CYTOSKELETON core and an INTEGRINS-containing ring complex.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Actin-rich adhesive structures found at the ventral surface of metazoan ENDOTHELIAL CELLS. When found in cultured cancer cells they are referred to as invadopodia. These are matrix-degrading structures composed of an ACTIN CYTOSKELETON core and an INTEGRINS-containing ring complex.

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Classification

Broader headings

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See Also

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Synonyms

6 entry terms
  • Invadopodia
  • Invadopodium
  • Invadosomes
  • Invadopodiums
  • Invadosome
  • Podosome

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

History Note

2016

MeSH Record

Previous Indexing

  • Cell Surface Extensions (2006-2015)
  • Extracellular Matrix (1996-2015)

MeSH Hierarchy

Tree Numbers

  1. A11w.284w.180.695w
  2. A11w.436.275.841w

AMA Style

References

  1. National Library of Medicine. Podosomes. Medical Subject Headings (MeSH). 2026. Unique ID D000069261. http://id.nlm.nih.gov/mesh/2026/D000069261
  2. Podosomes. In: Wikipedia. https://en.wikipedia.org/wiki/Podosome
  3. Podosomes. In: Wikidata. https://www.wikidata.org/wiki/Q7207063