Chemicals and Drugs

Polo-like Kinases

Protein serine-threonine kinases which regulate entry into M phase, spindle pole biogenesis and function, mitotic chromosome dynamics, mitotic exit, and cytokinesis. They contain a characteristic Polo-box protein interaction domain.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Protein serine-threonine kinases which regulate entry into M phase, spindle pole biogenesis and function, mitotic chromosome dynamics, mitotic exit, and cytokinesis. They contain a characteristic Polo-box protein interaction domain.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2024

MeSH Record

Previous Indexing

  • Protein Serine-Threonine Kinases (1993-2023)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.700w.616w
  2. D12.776w.167.469w
  3. D12.776w.476.563w.616w

AMA Style

References

  1. National Library of Medicine. Polo-like Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D000097868. http://id.nlm.nih.gov/mesh/2026/D000097868
  2. Polo-like Kinases. In: Wikipedia. https://en.wikipedia.org/wiki/Polo-like_kinase
  3. Polo-like Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q7225885