Chemicals and Drugs

Poloxamer

A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

40 entry terms
  • Pluronic
  • Pluronic F-108
  • Pluronic F-127
  • Pluronic F-68
  • Pluronic F68
  • Pluronic L-101
  • Pluronic L-121
  • Pluronic L-81
  • Pluronics
  • Poloxalkol
  • Poloxamer 188
  • Poloxamer 213
  • Poloxamer 2930
  • Poloxamer 338
  • Poloxamer 407
  • Poloxamers
  • 188s, Poloxamer
  • 213s, Poloxamer
  • 2930s, Poloxamer
  • 338s, Poloxamer
  • 407s, Poloxamer
  • F68s, Pluronic
  • Pluronic F 108
  • Pluronic F 127
  • Pluronic F 68
  • Pluronic F108
  • Pluronic F127
  • Pluronic F68s
  • Pluronic L 101
  • Pluronic L 121
  • Pluronic L 81
  • Pluronic L101
  • Pluronic L121
  • Pluronic L81
  • Poloxalkols
  • Poloxamer 188s
  • Poloxamer 213s
  • Poloxamer 2930s
  • Poloxamer 338s
  • Poloxamer 407s

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, chemical synthesis, chemistry, classification, economics, history, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity.

MeSH Record

History Note

1999; for POLOXAMERS use POLOXALENE 1974-1998

MeSH Record

Previous Indexing

  • Poloxalene (1976-1998)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Poloxamer. Medical Subject Headings (MeSH). 2026. Unique ID D020442. http://id.nlm.nih.gov/mesh/2026/D020442
  2. Poloxamer. In: Wikipedia. https://en.wikipedia.org/wiki/Poloxamer
  3. Poloxamer. In: Wikidata. https://www.wikidata.org/wiki/Q408943