Chemicals and Drugs

Poly(A)-Binding Protein I

A poly(A) binding protein that has a variety of functions such as mRNA stabilization and protection of RNA from nuclease activity. Although poly(A) binding protein I is considered a major cytoplasmic RNA-binding protein it is also found in the CELL NUCLEUS and may be involved in transport of mRNP particles.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A poly(A) binding protein that has a variety of functions such as mRNA stabilization and protection of RNA from nuclease activity. Although poly(A) binding protein I is considered a major cytoplasmic RNA-binding protein it is also found in the CELL NUCLEUS and may be involved in transport of mRNP particles.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

5 entry terms
  • PAB1 Poly(A) Binding Protein
  • PABP1 Protein
  • PABPC1 Protein
  • Poly(A)-Binding Protein, Cytoplasmic 1
  • p70 Poly(A) Binding Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2003; for P70 POLY(A) BINDING PROTEIN use POLY(A)-BINDING PROTEINS (NM) 1999-2002

MeSH Record

Previous Indexing

  • RNA-Binding Proteins (1993-2002)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Poly(A)-Binding Protein I. Medical Subject Headings (MeSH). 2026. Unique ID D039122. http://id.nlm.nih.gov/mesh/2026/D039122
  2. Poly(A)-Binding Protein I. In: Wikidata. https://www.wikidata.org/wiki/Q21126794