Chemicals and Drugs

Poly I-C

Interferon inducer consisting of a synthetic, mismatched double-stranded RNA. The polymer is made of one strand each of polyinosinic acid and polycytidylic acid.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Interferon inducer consisting of a synthetic, mismatched double-stranded RNA. The polymer is made of one strand each of polyinosinic acid and polycytidylic acid.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Poly(I-C)
  • Poly(rI).Poly(rC)
  • Polyinosinic-Polycytidylic Acid
  • Polyinosinic-Polycytidylic Acid (High MW)
  • Polyriboinosinic-Polyribocytidylic Acid
  • Polyribose Inosin-Cytidil
  • Inosin-Cytidil, Polyribose
  • Poly I C
  • Polyinosinic Polycytidylic Acid
  • Polyriboinosinic Polyribocytidylic Acid
  • Polyribose Inosin Cytidil

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse with POLY I

MeSH Record

History Note

73(71)

MeSH Record

Previous Indexing

  • Interferons/biosynthesis (1966-1970)
  • Polynucleotides (1966-1970)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Poly I-C. Medical Subject Headings (MeSH). 2026. Unique ID D011070. http://id.nlm.nih.gov/mesh/2026/D011070
  2. Poly I-C. In: Wikidata. https://www.wikidata.org/wiki/Q76832137