Chemicals and Drugs

Polyubiquitin

An oligomer formed from the repetitive linking of the C-terminal glycine of one UBIQUITIN molecule via an isopeptide bond to a lysine residue on a second ubiquitin molecule. It is structurally distinct from UBIQUITIN C, which is a single protein containing a tandemly arrayed ubiquitin peptide sequence.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An oligomer formed from the repetitive linking of the C-terminal glycine of one UBIQUITIN molecule via an isopeptide bond to a lysine residue on a second ubiquitin molecule. It is structurally distinct from UBIQUITIN C, which is a single protein containing a tandemly arrayed ubiquitin peptide sequence.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2002; use POLYUBIQUITIN (NM) 1991-2001

MeSH Record

Previous Indexing

  • Polymers (1991-1993)
  • Ubiquitins (1994-2001)

MeSH Hierarchy

Tree Number

  1. D12.776w.947.500w.500

AMA Style

References

  1. National Library of Medicine. Polyubiquitin. Medical Subject Headings (MeSH). 2026. Unique ID D025821. http://id.nlm.nih.gov/mesh/2026/D025821
  2. Polyubiquitin. In: Wikidata. https://www.wikidata.org/wiki/Q58514253