Structured Summary
Abstract
Toxic antibiotic of the mitomycin group, obtained from MITOMYCIN and also from Streptomyces ardus and other species. It is proposed as an antineoplastic agent, with some antibiotic properties.
Chemical Identity
Chemical Information
- Molecular Formula
- C16H20N4O5
- Molecular Weight
- 348.35 g/mol
- CAS Registry No.
- 801-52-5
- IUPAC Name
- [(4S,6S,7R,8S)-11-amino-7-methoxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
- InChIKey
- HRHKSTOGXBBQCB-VFWICMBZSA-N
- SMILES
- CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4C)N
- MeSH Unique ID
- D011160
- Source
- PubChem CID 13116
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
1 entry terms
- Methylmitomycin C
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(82)73; was see under MITOMYCINS 1982-90; was heading 1973-81
MeSH Record
Previous Indexing
- Antibiotics, Antineoplastic (1967-1972)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Porfiromycin. Medical Subject Headings (MeSH). 2026. Unique ID D011160. http://id.nlm.nih.gov/mesh/2026/D011160
- Porfiromycin. In: Wikipedia. https://en.wikipedia.org/wiki/Porfiromycin
- Porfiromycin. In: Wikidata. https://www.wikidata.org/wiki/Q27279527
- Porfiromycin. In: PubChem Compound. CID 13116. https://pubchem.ncbi.nlm.nih.gov/compound/13116