Phenomena and Processes

Postsynaptic Potential Summation

Physiological integration of multiple SYNAPTIC POTENTIAL signals to reach the threshold and initiate postsynaptic ACTION POTENTIALS. In spatial summation stimulations from additional synaptic junctions are recruited to generate s response. In temporal summation succeeding stimuli signals are summed up to reach the threshold. The postsynaptic potentials can be either excitatory or inhibitory (EPSP or IPSP).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Physiological integration of multiple SYNAPTIC POTENTIAL signals to reach the threshold and initiate postsynaptic ACTION POTENTIALS. In spatial summation stimulations from additional synaptic junctions are recruited to generate s response. In temporal summation succeeding stimuli signals are summed up to reach the threshold. The postsynaptic potentials can be either excitatory or inhibitory (EPSP or IPSP).

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

28 entry terms
  • Neurophysiology Summation
  • Post-Synaptic Potential Summation
  • Neurophysiology Summations
  • Post Synaptic Potential Summation
  • Post-Synaptic Potential Summations
  • Postsynaptic Potential Summations
  • Potential Summation, Post-Synaptic
  • Potential Summation, Postsynaptic
  • Potential Summations, Post-Synaptic
  • Potential Summations, Postsynaptic
  • Summation, Neurophysiology
  • Summation, Post-Synaptic Potential
  • Summation, Postsynaptic Potential
  • Summations, Neurophysiology
  • Summations, Post-Synaptic Potential
  • Summations, Postsynaptic Potential
  • Spatial Summation, Neurophysiology
  • Temporal Summation, Neurophysiology
  • Neurophysiology Spatial Summation
  • Neurophysiology Spatial Summations
  • Neurophysiology Temporal Summation
  • Neurophysiology Temporal Summations
  • Spatial Summations, Neurophysiology
  • Summation, Neurophysiology Spatial
  • Summation, Neurophysiology Temporal
  • Summations, Neurophysiology Spatial
  • Summations, Neurophysiology Temporal
  • Temporal Summations, Neurophysiology

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2012

MeSH Record

Previous Indexing

  • Synaptic Potentials (1969-2011)
  • Synaptic Transmission (1969-2011)

MeSH Hierarchy

Tree Numbers

  1. G02.111.820w.850.500w
  2. G04.580w.887w.750w
  3. G04.835w.850.500w
  4. G07.265.675w.887w.750w
  5. G07.265.880.750w.780w
  6. G11.561.570w.918w.750w
  7. G11.561.830.750w.780w

AMA Style

References

  1. National Library of Medicine. Postsynaptic Potential Summation. Medical Subject Headings (MeSH). 2026. Unique ID D059227. http://id.nlm.nih.gov/mesh/2026/D059227
  2. Postsynaptic Potential Summation. In: Wikipedia. https://en.wikipedia.org/wiki/Summation_(neurophysiology)
  3. Postsynaptic Potential Summation. In: Wikidata. https://www.wikidata.org/wiki/Q2365287