Chemicals and Drugs

Pralidoxime Compounds

Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • 2-PAM Compounds
  • Pyridine Aldoxime Methyl Compounds
  • 2 PAM Compounds
  • Compounds, 2-PAM
  • Compounds, Pralidoxime

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

65(63)

MeSH Hierarchy

Tree Number

  1. D02w.092w.570.665w.535

AMA Style

References

  1. National Library of Medicine. Pralidoxime Compounds. Medical Subject Headings (MeSH). 2026. Unique ID D011220. http://id.nlm.nih.gov/mesh/2026/D011220
  2. Pralidoxime Compounds. In: Wikidata. https://www.wikidata.org/wiki/Q75006996