Chemicals and Drugs

Pre-beta High-Density Lipoproteins

A highly dense subclass of the high-density lipoproteins, with particle sizes below 7 nm. They are also known as nascent HDL, composed of a few APOLIPOPROTEIN A-I molecules which are complexed with PHOSPHOLIPIDS. The lipid-poor pre-beta-HDL particles serve as progenitors of HDL3 and then HDL2 after absorption of free cholesterol from cell membranes, cholesterol esterification, and acquisition of apolipoproteins A-II, Cs, and E. Pre-beta-HDL initiate the reverse cholesterol transport process from cells to liver.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A highly dense subclass of the high-density lipoproteins, with particle sizes below 7 nm. They are also known as nascent HDL, composed of a few APOLIPOPROTEIN A-I molecules which are complexed with PHOSPHOLIPIDS. The lipid-poor pre-beta-HDL particles serve as progenitors of HDL3 and then HDL2 after absorption of free cholesterol from cell membranes, cholesterol esterification, and acquisition of apolipoproteins A-II, Cs, and E. Pre-beta-HDL initiate the reverse cholesterol transport process from cells to liver.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

24 entry terms
  • High-Density Lipoproteins, Pre-beta
  • Lipoprotein, Pre-beta HDL
  • Nascent HDL
  • Pre-beta HDL
  • Pre-beta High-Density Lipoprotein
  • PreBeta-HDL
  • HDL Lipoprotein, Pre-beta
  • HDL, Nascent
  • HDL, Pre-beta
  • High Density Lipoproteins, Pre beta
  • High-Density Lipoprotein, Pre-beta
  • Lipoprotein, Pre beta HDL
  • Lipoproteins, Pre-beta High-Density
  • Pre beta HDL
  • Pre beta High Density Lipoprotein
  • Pre-beta HDL Lipoprotein
  • PreBeta HDL
  • High-Density Lipoprotein, Pre-beta1
  • Pre-beta1 HDL
  • Pre-beta1 High-Density Lipoprotein
  • HDL, Pre-beta1
  • High Density Lipoprotein, Pre beta1
  • Pre beta1 HDL
  • Pre beta1 High Density Lipoprotein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007 (1992)

MeSH Record

Previous Indexing

  • Lipoproteins, HDL (1990-2006)

MeSH Hierarchy

Tree Numbers

  1. D10w.532w.432w.550
  2. D12.776w.521w.479w.602

AMA Style

References

  1. National Library of Medicine. Pre-beta High-Density Lipoproteins. Medical Subject Headings (MeSH). 2026. Unique ID D053442. http://id.nlm.nih.gov/mesh/2026/D053442
  2. Pre-beta High-Density Lipoproteins. In: Wikidata. https://www.wikidata.org/wiki/Q77182976