Chemicals and Drugs

Pregnanetriol

A metabolite of 17-ALPHA-HYDROXYPROGESTERONE, normally produced in small quantities by the GONADS and the ADRENAL GLANDS, found in URINE. An elevated urinary pregnanetriol is associated with CONGENITAL ADRENAL HYPERPLASIA with a deficiency of STEROID 21-HYDROXYLASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A metabolite of 17-ALPHA-HYDROXYPROGESTERONE, normally produced in small quantities by the GONADS and the ADRENAL GLANDS, found in URINE. An elevated urinary pregnanetriol is associated with CONGENITAL ADRENAL HYPERPLASIA with a deficiency of STEROID 21-HYDROXYLASE.

Chemical Identity

Chemical Information

Molecular Formula
C21H36O3
Molecular Weight
336.5 g/mol
CAS Registry No.
1098-45-9
IUPAC Name
(3R,5R,8R,9S,10S,13S,14S,17R)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol
InChIKey
SCPADBBISMMJAW-UHHUKTEYSA-N
SMILES
C[C@@H]([C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C)O)O
MeSH Unique ID
D011279
Source
PubChem CID 101967

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

2 entry terms
  • 5-beta-Pregnane-3,17,20-triol
  • 5beta-Pregnane-3alpha,17alpha,20alpha-triol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

66(64)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

WP 530

AMA Style

References

  1. National Library of Medicine. Pregnanetriol. Medical Subject Headings (MeSH). 2026. Unique ID D011279. http://id.nlm.nih.gov/mesh/2026/D011279
  2. Pregnanetriol. In: Wikipedia. https://en.wikipedia.org/wiki/Pregnanetriol
  3. Pregnanetriol. In: Wikidata. https://www.wikidata.org/wiki/Q7239897
  4. Pregnanetriol. In: PubChem Compound. CID 101967. https://pubchem.ncbi.nlm.nih.gov/compound/101967