Chemicals and Drugs

Pregnenolone

A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.

Chemical Identity

Chemical Information

Molecular Formula
C21H32O2
Molecular Weight
316.5 g/mol
CAS Registry No.
145-13-1
IUPAC Name
1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
InChIKey
ORNBQBCIOKFOEO-QGVNFLHTSA-N
SMILES
CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C
MeSH Unique ID
D011284
Source
PubChem CID 8955

MeSH Record

Classification

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

2 entry terms
  • 5-Pregnen-3-beta-ol-20-one
  • 5 Pregnen 3 beta ol 20 one

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse with PREGNANOLONE

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Pregnenolone. Medical Subject Headings (MeSH). 2026. Unique ID D011284. http://id.nlm.nih.gov/mesh/2026/D011284
  2. Pregnenolone. In: Wikipedia. https://en.wikipedia.org/wiki/Pregnenolone
  3. Pregnenolone. In: Wikidata. https://www.wikidata.org/wiki/Q412158
  4. Pregnenolone. In: PubChem Compound. CID 8955. https://pubchem.ncbi.nlm.nih.gov/compound/8955