Chemicals and Drugs

Prenylamine

A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1406)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1406)

Chemical Identity

Chemical Information

Molecular Formula
C24H27N
Molecular Weight
329.5 g/mol
CAS Registry No.
390-64-7
IUPAC Name
3,3-diphenyl-N-(1-phenylpropan-2-yl)propan-1-amine
InChIKey
IFFPICMESYHZPQ-UHFFFAOYSA-N
SMILES
CC(CC1=CC=CC=C1)NCCC(C2=CC=CC=C2)C3=CC=CC=C3
MeSH Unique ID
D011299
Source
PubChem CID 9801

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Corontin
  • Difril
  • Segontin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

66; was SEGONTIN 1963-65

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Prenylamine. Medical Subject Headings (MeSH). 2026. Unique ID D011299. http://id.nlm.nih.gov/mesh/2026/D011299
  2. Prenylamine. In: Wikipedia. https://en.wikipedia.org/wiki/Prenylamine
  3. Prenylamine. In: Wikidata. https://www.wikidata.org/wiki/Q7240579
  4. Prenylamine. In: PubChem Compound. CID 9801. https://pubchem.ncbi.nlm.nih.gov/compound/9801