Diseases

Primary Myelofibrosis

A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

28 entry terms
  • Agnogenic Myeloid Metaplasia
  • Bone Marrow Fibrosis
  • Chronic Idiopathic Myelofibrosis
  • Fibrosis, Bone Marrow
  • Idiopathic Myelofibrosis
  • Myelofibrosis
  • Myelofibrosis With Myeloid Metaplasia
  • Myeloid Metaplasia
  • Myelosclerosis
  • Myelosis, Nonleukemic
  • Agnogenic Myeloid Metaplasias
  • Bone Marrow Fibroses
  • Fibroses, Bone Marrow
  • Metaplasia, Agnogenic Myeloid
  • Metaplasia, Myeloid
  • Metaplasias, Agnogenic Myeloid
  • Metaplasias, Myeloid
  • Myelofibroses
  • Myelofibroses, Primary
  • Myelofibrosis, Primary
  • Myeloid Metaplasia, Agnogenic
  • Myeloid Metaplasias
  • Myeloid Metaplasias, Agnogenic
  • Myeloscleroses
  • Myeloses, Nonleukemic
  • Nonleukemic Myeloses
  • Nonleukemic Myelosis
  • Primary Myelofibroses

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2009

MeSH Record

Previous Indexing

  • Myelofibrosis (1963-2008)

MeSH Hierarchy

Tree Number

  1. C15.378w.190.636w.765w

MeSH Record

NLM Classification

WH 385

AMA Style

References

  1. National Library of Medicine. Primary Myelofibrosis. Medical Subject Headings (MeSH). 2026. Unique ID D055728. http://id.nlm.nih.gov/mesh/2026/D055728
  2. Primary Myelofibrosis. In: Wikipedia. https://en.wikipedia.org/wiki/Primary_myelofibrosis
  3. Primary Myelofibrosis. In: Wikidata. https://www.wikidata.org/wiki/Q1752571