Chemicals and Drugs

Primidone

A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.

Chemical Identity

Chemical Information

Molecular Formula
C12H14N2O2
Molecular Weight
218.25 g/mol
CAS Registry No.
125-33-7
IUPAC Name
5-ethyl-5-phenyl-1,3-diazinane-4,6-dione
InChIKey
DQMZLTXERSFNPB-UHFFFAOYSA-N
SMILES
CCC1(C(=O)NCNC1=O)C2=CC=CC=C2
MeSH Unique ID
D011324
Source
PubChem CID 4909

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • Apo-Primidone
  • Desoxyphenobarbital
  • Liskantin
  • Misodine
  • Mizodin
  • Mylepsinum
  • Mysoline
  • Primaclone
  • Primidon Holsten
  • Resimatil
  • Sertan
  • Apo Primidone

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Primidone. Medical Subject Headings (MeSH). 2026. Unique ID D011324. http://id.nlm.nih.gov/mesh/2026/D011324
  2. Primidone. In: Wikipedia. https://en.wikipedia.org/wiki/Primidone
  3. Primidone. In: Wikidata. https://www.wikidata.org/wiki/Q420383
  4. Primidone. In: PubChem Compound. CID 4909. https://pubchem.ncbi.nlm.nih.gov/compound/4909