Chemicals and Drugs

Probucol

A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).

Chemical Identity

Chemical Information

Molecular Formula
C31H48O2S2
Molecular Weight
516.8 g/mol
CAS Registry No.
23288-49-5
IUPAC Name
2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenol
InChIKey
FYPMFJGVHOHGLL-UHFFFAOYSA-N
SMILES
CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C
MeSH Unique ID
D011341
Source
PubChem CID 4912

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Biphenabid
  • DH-581
  • Lorelco
  • Lurselle
  • Panavir
  • Superlipid
  • DH 581
  • DH581

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(73); was see under PHENOLS 1973-90

MeSH Record

Previous Indexing

  • Anticholesteremic Agents (1966-1972)
  • Phenols (1966-1972)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Probucol. Medical Subject Headings (MeSH). 2026. Unique ID D011341. http://id.nlm.nih.gov/mesh/2026/D011341
  2. Probucol. In: Wikipedia. https://en.wikipedia.org/wiki/Probucol
  3. Probucol. In: Wikidata. https://www.wikidata.org/wiki/Q10354103
  4. Probucol. In: PubChem Compound. CID 4912. https://pubchem.ncbi.nlm.nih.gov/compound/4912