Structured Summary
Abstract
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Chemical Identity
Chemical Information
- Molecular Formula
- C12H19N3O
- Molecular Weight
- 221.30 g/mol
- CAS Registry No.
- 671-16-9
- IUPAC Name
- 4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide
- InChIKey
- CPTBDICYNRMXFX-UHFFFAOYSA-N
- SMILES
- CC(C)NC(=O)C1=CC=C(C=C1)CNNC
- MeSH Unique ID
- D011344
- Source
- PubChem CID 4915
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- Matulane
- Natulan
- Procarbazine Hydrochloride
- Procarbazine Monohydrobromide
- Procarbazine Monohydrochloride
- Hydrochloride, Procarbazine
- Monohydrobromide, Procarbazine
- Monohydrochloride, Procarbazine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
74(71)
MeSH Record
Previous Indexing
- Antineoplastic Agents (1966-1970)
- Benzoates (1966-1970)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Procarbazine. Medical Subject Headings (MeSH). 2026. Unique ID D011344. http://id.nlm.nih.gov/mesh/2026/D011344
- Procarbazine. In: Wikipedia. https://en.wikipedia.org/wiki/Procarbazine
- Procarbazine. In: Wikidata. https://www.wikidata.org/wiki/Q418656
- Procarbazine. In: PubChem Compound. CID 4915. https://pubchem.ncbi.nlm.nih.gov/compound/4915