Chemicals and Drugs

Prodrugs

A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.

MeSH Record

Classification

Narrower headings

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • Drug Precursor
  • Drug Precursors
  • Pro-Drug
  • Pro-Drugs
  • Prodrug
  • Precursor, Drug
  • Precursors, Drug
  • Pro Drug
  • Pro Drugs

MeSH Record

Aspects Covered

18 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, chemical synthesis, chemistry, classification, economics, history, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity.

MeSH Record

Indexing Annotation

coordinate with specific drug

MeSH Record

History Note

89(88); was see under DRUGS 1988

MeSH Record

Previous Indexing

  • Delayed-Action Preparations (1966-1987)

MeSH Hierarchy

Tree Number

  1. D26.675w

MeSH Record

NLM Classification

QV 785

AMA Style

References

  1. National Library of Medicine. Prodrugs. Medical Subject Headings (MeSH). 2026. Unique ID D011355. http://id.nlm.nih.gov/mesh/2026/D011355
  2. Prodrugs. In: Wikipedia. https://en.wikipedia.org/wiki/Prodrug
  3. Prodrugs. In: Wikidata. https://www.wikidata.org/wiki/Q603741