Structured Summary
Abstract
The common precursor polypeptide of pancreatic GLUCAGON and intestinal GLUCAGON-LIKE PEPTIDES. Proglucagon is the 158-amino acid segment of preproglucagon without the N-terminal signal sequence. Proglucagon is expressed in the PANCREAS; INTESTINES; and the CENTRAL NERVOUS SYSTEM. Posttranslational processing of proglucagon is tissue-specific yielding numerous bioactive peptides.
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Synonyms
7 entry terms
- Pro-Glucagon
- Pro Glucagon
- Glucagon Precursor
- Glucagon Precursors
- Pre-Proglucagons
- Preproglucagon
- Preproglucagons
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007 (2006); for GLUCAGON PRECURSOR use GLUCAGON PRECURSOR (NM) 1977-2007
MeSH Record
Previous Indexing
- Enteroglucagon (1982-2005)
- Glucagon (1973-2005)
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References
- National Library of Medicine. Proglucagon. Medical Subject Headings (MeSH). 2026. Unique ID D052336. http://id.nlm.nih.gov/mesh/2026/D052336
- Proglucagon. In: Wikipedia. https://en.wikipedia.org/wiki/Proglucagon
- Proglucagon. In: Wikidata. https://www.wikidata.org/wiki/Q66310097