Chemicals and Drugs

Proglumide

A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.

Chemical Identity

Chemical Information

Molecular Formula
C18H26N2O4
Molecular Weight
334.4 g/mol
CAS Registry No.
6620-60-6
IUPAC Name
4-benzamido-5-(dipropylamino)-5-oxopentanoic acid
InChIKey
DGMKFQYCZXERLX-UHFFFAOYSA-N
SMILES
CCCN(CCC)C(=O)C(CCC(=O)O)NC(=O)C1=CC=CC=C1
MeSH Unique ID
D011377
Source
PubChem CID 4922

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Xilamide
  • Xylamide
  • Milid

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under GLUTAMINE 1975-90

MeSH Record

Previous Indexing

  • Benzamides (1974)
  • Glutamine (1972-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Proglumide. Medical Subject Headings (MeSH). 2026. Unique ID D011377. http://id.nlm.nih.gov/mesh/2026/D011377
  2. Proglumide. In: Wikipedia. https://en.wikipedia.org/wiki/Proglumide
  3. Proglumide. In: Wikidata. https://www.wikidata.org/wiki/Q7248362
  4. Proglumide. In: PubChem Compound. CID 4922. https://pubchem.ncbi.nlm.nih.gov/compound/4922