Structured Summary
Abstract
Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes.
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Classification
Broader headings
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Synonyms
10 entry terms
- PML Bodies
- PML NBs
- PML Nuclear Bodies
- Promyelocytic Leukemia Nuclear Body
- Promyelocytic Leukemia Protein Bodies
- Promyelocytic Leukemia Protein Body
- Nuclear Bodies, PML
- Nuclear Body, PML
- PML Body
- PML Nuclear Body
MeSH Record
Aspects Covered
15 allowable subheadings
Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.
MeSH Record
History Note
2022
MeSH Record
Previous Indexing
- Intranuclear Inclusion Bodies (2008-2021)
- Promyelocytic Leukemia Protein (2008-2021)
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References
- National Library of Medicine. Promyelocytic Leukemia Nuclear Bodies. Medical Subject Headings (MeSH). 2026. Unique ID D000088182. http://id.nlm.nih.gov/mesh/2026/D000088182
- Promyelocytic Leukemia Nuclear Bodies. In: Wikidata. https://www.wikidata.org/wiki/Q14817968