Structured Summary
Abstract
A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.
MeSH Record
Classification
Related Concepts
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MeSH Record
Synonyms
2 entry terms
- RNF71 Protein
- TRIM19 Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- Nuclear Proteins (2008-2016)
- Transcription Factors (2008-2016)
- Tumor Suppressor Proteins (2008-2016)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Promyelocytic Leukemia Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000071156. http://id.nlm.nih.gov/mesh/2026/D000071156
- Promyelocytic Leukemia Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21106974