Chemicals and Drugs

Propafenone

An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.

Chemical Identity

Chemical Information

Molecular Formula
C21H27NO3
Molecular Weight
341.4 g/mol
CAS Registry No.
54063-53-5
IUPAC Name
1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one
InChIKey
JWHAUXFOSRPERK-UHFFFAOYSA-N
SMILES
CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O
MeSH Unique ID
D011405
Source
PubChem CID 4932

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

28 entry terms
  • Apo-Propafenone
  • Arythmol
  • Baxarytmon
  • Cuxafenon
  • Fenoprain
  • Jutanorm
  • Nistaken
  • Norfenon
  • Pintoform
  • Prolecofen
  • Propafenon AL
  • Propafenon Hexal
  • Propafenon Minden
  • Propafenone Hydrochloride
  • Propafenone Hydrochloride, (R)-Isomer
  • Propafenone Hydrochloride, (S)-Isomer
  • Propafenone, (+-)-Isomer
  • Propafenone, (R)-Isomer
  • Propafenone, (S)-Isomer
  • Propamerck
  • Rythmol
  • Rytmo-Puren
  • Rytmogenat
  • Rytmonorm
  • SA-79
  • Hydrochloride, Propafenone
  • SA 79
  • SA79

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Propiophenones (1966-1986)

MeSH Hierarchy

Tree Number

  1. D02w.522w.818.830w

MeSH Record

NLM Classification

QV 152

AMA Style

References

  1. National Library of Medicine. Propafenone. Medical Subject Headings (MeSH). 2026. Unique ID D011405. http://id.nlm.nih.gov/mesh/2026/D011405
  2. Propafenone. In: Wikipedia. https://en.wikipedia.org/wiki/Propafenone
  3. Propafenone. In: Wikidata. https://www.wikidata.org/wiki/Q662511
  4. Propafenone. In: PubChem Compound. CID 4932. https://pubchem.ncbi.nlm.nih.gov/compound/4932