Structured Summary
Abstract
Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Chemical Identity
Chemical Information
- Molecular Formula
- C27H34N4+2
- Molecular Weight
- 414.6 g/mol
- CAS Registry No.
- 36015-30-2
- IUPAC Name
- 3-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propyl-diethyl-methylazanium
- InChIKey
- ZDWVWKDAWBGPDN-UHFFFAOYSA-O
- SMILES
- CC[N+](C)(CC)CCC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N
- MeSH Unique ID
- D011419
- Source
- PubChem CID 4939
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- Propidium Diiodide
- Propidium Iodide
- Diiodide, Propidium
- Iodide, Propidium
MeSH Record
Aspects Covered
19 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, chemical synthesis, chemistry, classification, economics, history, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity.
MeSH Record
History Note
91(79); was see under PHENANTHRIDINES 1979-90
MeSH Record
Previous Indexing
- Ethidium (1974-1978)
- Phenanthridines (1969-1978)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Propidium. Medical Subject Headings (MeSH). 2026. Unique ID D011419. http://id.nlm.nih.gov/mesh/2026/D011419
- Propidium. In: Wikidata. https://www.wikidata.org/wiki/Q27093226
- Propidium. In: PubChem Compound. CID 4939. https://pubchem.ncbi.nlm.nih.gov/compound/4939