Chemicals and Drugs

Propofol

An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.

Chemical Identity

Chemical Information

Molecular Formula
C12H18O
Molecular Weight
178.27 g/mol
CAS Registry No.
2078-54-8
IUPAC Name
2,6-di(propan-2-yl)phenol
InChIKey
OLBCVFGFOZPWHH-UHFFFAOYSA-N
SMILES
CC(C)C1=C(C(=CC=C1)C(C)C)O
MeSH Unique ID
D015742
Source
PubChem CID 4943

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

21 entry terms
  • 2,6-Bis(1-methylethyl)phenol
  • 2,6-Diisopropylphenol
  • Disoprofol
  • 2,6 Diisopropylphenol
  • Aquafol
  • Diprivan
  • Disoprivan
  • Fresofol
  • ICI-35,868
  • ICI-35868
  • Ivofol
  • Propofol Abbott
  • Propofol Fresenius
  • Propofol MCT
  • Propofol Rovi
  • Propofol-Lipuro
  • Recofol
  • ICI 35,868
  • ICI 35868
  • ICI35,868
  • ICI35868

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Analgesics, Narcotic (1975-1989)
  • Anesthetics (1966-1989)
  • Phenols (1966-1989)
  • Sedatives, Nonbarbiturate (1975-1989)

MeSH Hierarchy

Tree Number

  1. D02w.455w.426w.559w.389.657w.773w

AMA Style

References

  1. National Library of Medicine. Propofol. Medical Subject Headings (MeSH). 2026. Unique ID D015742. http://id.nlm.nih.gov/mesh/2026/D015742
  2. Propofol. In: Wikipedia. https://en.wikipedia.org/wiki/Propofol
  3. Propofol. In: Wikidata. https://www.wikidata.org/wiki/Q422740
  4. Propofol. In: PubChem Compound. CID 4943. https://pubchem.ncbi.nlm.nih.gov/compound/4943