Structured Summary
Abstract
A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Chemical Identity
Chemical Information
- Molecular Formula
- C7H10N2OS
- Molecular Weight
- 170.23 g/mol
- CAS Registry No.
- 51-52-5
- IUPAC Name
- 6-propyl-2-sulfanylidene-1H-pyrimidin-4-one
- InChIKey
- KNAHARQHSZJURB-UHFFFAOYSA-N
- SMILES
- CCCC1=CC(=O)NC(=S)N1
- MeSH Unique ID
- D011441
- Source
- PubChem CID 657298
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
2 entry terms
- 6-Propyl-2-Thiouracil
- 6 Propyl 2 Thiouracil
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
a thyroid antag
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Propylthiouracil. Medical Subject Headings (MeSH). 2026. Unique ID D011441. http://id.nlm.nih.gov/mesh/2026/D011441
- Propylthiouracil. In: Wikipedia. https://en.wikipedia.org/wiki/Propylthiouracil
- Propylthiouracil. In: Wikidata. https://www.wikidata.org/wiki/Q377342
- Propylthiouracil. In: PubChem Compound. CID 657298. https://pubchem.ncbi.nlm.nih.gov/compound/657298