Structured Summary
Abstract
A serine endopeptidase that has a similar cleavage specificity to TRYPSIN, favoring substrates with poly-basic amino acid sequences. Prostasin plays a critical role in activating EPITHELIAL SODIUM CHANNELS through cleavage of the ENAC gamma subunit.
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Broader headings
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Synonyms
1 entry terms
- Serine Protease 8
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2026 (1994)
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AMA Style
References
- National Library of Medicine. Prostasin. Medical Subject Headings (MeSH). 2026. Unique ID D000099271. http://id.nlm.nih.gov/mesh/2026/D000099271
- Prostasin. In: Wikidata. https://www.wikidata.org/wiki/Q21133527