Chemicals and Drugs

Protein Disulfide Reductase (Glutathione)

An enzyme that catalyzes the reduction of a protein-disulfide in the presence of glutathione, forming a protein-dithiol. Insulin is one of its substrates. EC 1.8.4.2.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the reduction of a protein-disulfide in the presence of glutathione, forming a protein-dithiol. Insulin is one of its substrates. EC 1.8.4.2.

MeSH Record

Classification

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MeSH Record

Synonyms

11 entry terms
  • Glutathione Insulin Transhydrogenase
  • Glutathione Protein Disulfide Oxidoreductase
  • Thiol-Protein Disulfide Oxidoreductase
  • Disulfide Oxidoreductase, Thiol-Protein
  • Insulin Transhydrogenase, Glutathione
  • Oxidoreductase, Thiol-Protein Disulfide
  • Thiol Protein Disulfide Oxidoreductase
  • Transhydrogenase, Glutathione Insulin
  • Thiol-Disulfide Oxidoreductase
  • Oxidoreductase, Thiol-Disulfide
  • Thiol Disulfide Oxidoreductase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(75); was see under OXIDOREDUCTASES 1975-90

MeSH Record

Previous Indexing

  • Glutathione (1972-1974)
  • Glutathione Reductase (1974)
  • Insulin (1972-1974)
  • Oxidoreductases (1972-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Protein Disulfide Reductase (Glutathione). Medical Subject Headings (MeSH). 2026. Unique ID D011490. http://id.nlm.nih.gov/mesh/2026/D011490
  2. Protein Disulfide Reductase (Glutathione). In: Wikipedia. https://en.wikipedia.org/wiki/Protein-disulfide_reductase_(glutathione)
  3. Protein Disulfide Reductase (Glutathione). In: Wikidata. https://www.wikidata.org/wiki/Q3597048